Prevalence of Drug Resistant Uropathogenes In General Hospitals

Abstract

Background: Globally, urinary tract infection(UTI) is the most common type of disease in the human body and bacterial infection is the most common, as has the most urinary inflammation causing bacteria occur when it colonizes in the urinary tract and remains a major public health issue. The appropriate diagnostic criterion for UTI is urinalysis and the culture of urine.

Objective: This research attempted to evaluate the efficiency of the specific causative agents, as well as evaluating their susceptibility to antibiotic trends.

Patients & Methods: A cross sectional study was held out at our general-hospital among UTI cases. Bacterial uropathogens were isolated, identified and antimicrobial  susceptibility tests were executed using the disc diffusion technique described by Kirby-Bauer.

Results: In this study  is revealed that UTI (53.8% )486/903 of urine specimens had resulted in positive culture for bacteria. The most serious illness is urinary tract infection, an infection in women approximately 82.9%. the most prevalent pathogen was E. coli(39.9%), followed by Staphylococcus spp. 22.8%(S. aureus 11.5% and S. saprophyticus 11.3%) and Klebsiella spp. 14.1%. Most of the resistant drug against bacterial uropathogens, Cefixime (77.3%), Trimethoprim (77.1%) and Trimethoprim/Sulfamethoxazole(73.5% ). Besides, meropenem resistance rate (13.1%).

Conclusions: Formerly a course of oral Trimethoprim/ Sulfamethoxazole were the treatment of choice to UTIs, but because of increasing resistance, it is now only recommended if uropathogens low resistance rates. Recommended empirical treatment of acute uncomplicated UTIs is a course of Nitrofurantoin. Moreover, The carbapenem-resistant insulation from UTIs should be assessed carefully, because their occurrence suggests probable produce of carbapenemases by uropathogenes into the country, therefore, meropenem could be use compelled by  at hospitals levels